Advising -- See your advisor early each semester before pre-registering for the next semester to be sure you take the right courses to meet your program's requirements in the most efficient way. Your advisor can give you ideas about possible careers and graduate programs.
Support -- There are specific offices that can provide you with additional help, whether for difficult course (Academic Success Center), a personal issue (Counseling Center), the cost of going to school (Financial Aid Office), or any other issues.
Knowledge -- Focus on your academic courses. Go to all your classes. Meet with your instructors during their office hours. Study two hours each week for every hour you spend in class (i.e. 15 credits of courses = 30 hours of studying each week).